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Elton Vasconcelos

Dr Elton Vasconcelos is a Senior Bioinformatics Research Officer from Leeds Omics at the University of Leeds. He received his PhD degree in Cell and Molecular Biology (Aug. 2011 at the School of Medicine of Ribeirao Preto, University of Sao Paulo, Brazil), and was awarded with two personal postdoctoral fellowship grants approved for working in the fields of Omics and Bioinformatics applied to public health-impacting pathogens (Jan. 2013 - Dec. 2014 at Center for Infectious Disease Research, Seattle, WA, USA, and Jan. 2015 – Dec. 2016 at Institute of Chemistry, University of Sao Paulo, Brazil). Before joining Leeds Omics in Feb. 2019, he spent two years in California working as a key bioinformatician responsible for building a computational workflow for microbial community analysis in Veterinary Medicine (Jan. 2017 – Jan. 2019, College of Veterinary Medicine, Western University of Health Sciences, Pomona, CA, USA).

For over 10 years, Dr Vasconcelos has been deeply involved in computational approaches, aiming scrutinizing target organisms’ genomes and transcriptomes, as well as investigating microbiomes from clinical samples,  by adopting different high-throughput sequencing strategies and their respective downstream analyses. He has become Unix proficient and acquired advanced skills on programming languages such as PERL and R. His strong dual background in Molecular Biology and Bioinformatics, summed with his collaborations with researchers from Brazil and the USA, make him totally capable of developing basic research programs, as well as performing as many collaborative efforts as possible in the field of Computational Omics.

Areas of expertise: Bioinformatics data analyses on Genomics, Metagenomics, Transcriptomics, and Proteomics.

Other useful links: University Profile, Web of Science, ResearchGate, Github


Selected publications:

MURPHY JC, HARRINGTON EM, SCHUMANN S, VASCONCELOS EJR, MOTTRAM TJ, HARPER KL, ASPDEN JL, WHITEHOUSE A.  Kaposi’s sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs. Nature Communications. 2023. PMID: 36653366 

MARAN SR, FLECK K, MONTEIRO-TELES NM, ISEBE T, WALRAD P, JEFFERS V, CESTARI I, VASCONCELOS EJR, MORETTI N. Protein acetylation in the critical biological processes in protozoan parasites. Trends Parasitol2021. PMID: 33994102

MOREA EGO, VASCONCELOS EJR, DE SANTIS ALVES C, GIORGIO S, MYLER PJ, LANGONI H, AZZALIN CM, CANO MIN. Exploring TERRA during Leishmania major developmental cycle and continuous in vitro passages. Int J Biol Macromol, 2021. PMID: 33548324

LARA-REYNA S, POULTER JA, VASCONCELOS EJR, KACAR M, MCDERMOTT MF, TOOZE R, DOFFINGER R, SAVIC S. Identification of Critical Transcriptomic Signaling Pathways in Patients with H Syndrome and Rosai-Dorfman Disease. J Clin Immunol, 2021. PMID: 33284430

DRECHSLER Y§, VASCONCELOS EJR§, GRIGGS LM, DINIZ PPPV. CRFK and Primary Macrophages Transcriptomes in Response to Feline Coronavirus Infection Differ Significantly. Frontiers in Genetics, 2020. § Co-corresponding and co-1st authorship. PMID: 33343631

DRECHSLER Y§, VASCONCELOS EJR§, GRIGGS LM, DINIZ PPPV, COLLISSON E. Host Gene Expression of Macrophages in Response to Feline Coronavirus Infection. Cells, 2020. § Co-corresponding and co-1st authorship. PMID: 32526950

RUY PC, MONTEIRO-TELES NM, MISERANI MAGALHÃES RD, FREITAS-CASTRO F, DIAS L, AQUINO DEFINA TP, ROSAS DE VASCONCELOS EJ, MYLER PJ, KAYSEL CRUZ A. Comparative transcriptomics in Leishmania braziliensis: disclosing differential gene expression of coding and putative noncoding RNAs across developmental stages. RNA Biology, 2019. PMID: 30689499 

VASCONCELOS, EJR; BILLETER, SA; JETT, LA; MEINERSMANN, RJ; BARR, MC; DINIZ, PPVP; OAKLEY, BB. Assessing cat flea microbiomes in northern and southern California by 16S rRNA Next Generation Sequencing. Vector-Borne and Zoonotic Diseases, 2018. PMID: 29893631

OAKLEY BB, VASCONCELOS EJR, DINIZ PPVP, CALLOWAY KN, RICHARDSON E, MEINERSMANN RJ, COX NA, BERRANG ME. The cecal microbiome of commercial broiler chickens varies significantly by season. Poultry Science, 2018. PMID: 30016503

VASCONCELOS EJR *, MESEL VC, SILVA LF, PIRES DS, LAVEZZO GM, PEREIRA ASA, AMARAL MS, VERJOVSKI-ALMEIDA S. Atlas of Schistosoma mansoni long non-coding RNAs and their expression correlation to protein-coding genes. Database, 2018. * Corresponding author. PMID: 29992321

VASCONCELOS, E. J. R.; SILVA, L. F.; PIRES, D. S.; LAVEZZO, G.; PEREIRA, A. S.; AMARAL, M. S.; VERJOVSKI-ALMEIDA, S. . The Schistosoma mansoni genome encodes thousands of long non-coding RNAs predicted to be functional at different parasite life-cycle stages. Scientific Reports, 2017. PMID: 28874839

TERRÃO M. C.; ROSAS DE VASCONCELOS E. J.; DEFINA T. A.; MYLER P. J.; CRUZ A. K. . Disclosing 3' UTR cis-elements and putative partners involved in gene expression regulation in Leishmania spp. PLoS One, 2017. PMID: 28859096

LAMBERTZ, U. ; OVANDO, M. O. ; VASCONCELOS, E. J. R. ; UNRAU, P. J. ; MYLER, P. J. ; REINER, N. E. . Small RNAs Derived From tRNAs and rRNAs Are Highly Enriched in Exosomes From Both Old and New World Leishmania Providing Evidence For Conserved Exosomal RNA Packaging. BMC Genomics, v. 16, p. 151, 2015. PMID: 25764986

VASCONCELOS, E. J. R. ; NUNES, V. S. ; SILVA, M. S. ; SEGATTO, M. ; MYLER, P. J. ; CANO, M. I. N. . The Putative Leishmania Telomerase RNA (LeishTER) Undergoes Trans-Splicing and Contains a Conserved Template Sequence. PLoS One, 2014. PMID: 25391020

JENSEN, B. C. ; RAMASAMY, G. ; VASCONCELOS, E. J. R. ; INGOLIA, N. T. ; MYLER, P. J. ; PARSONS, M. . Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma brucei. BMC Genomics, v. 15, p. 911, 2014. PMID: 25331479

VASCONCELOS, E. J. R.; TERRÃO, M. C.; RUIZ, J. C.; VÊNCIO, R. Z. N.; CRUZ, A.K.. In silico identification of conserved intercoding sequences in Leishmania genomes: Unraveling putative cis-regulatory elements. Molecular and Biochemical Parasitology, 2012 Jun;183(2):140-50. PMID: 22387760.

For a complete list of my publications, please click here.