Selected LeedsOmics-related publications
2023. A Practical Guide to 16S rRNA Microbiome Analysis in Musculoskeletal Disorders. , pp. 85-105
2023. From Genomics to Metagenomics in the Era of Recent Sequencing Technologies. , pp. 1-20
2023. Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress. Liver International.
2023. Metabolic Drivers of Dysglycemia in Pregnancy: Ethnic-Specific GWAS of 146 Metabolites and 1-Sample Mendelian Randomisation Analyses in a UK Multi-Ethnic Birth Cohort. Frontiers in Endocrinology.
2023. A burst of genomic innovation at the origin of placental mammals mediated embryo implantation. Communications Biology. 6
2023. Infection‐induced extracellular vesicles evoke neuronal transcriptional and epigenetic changes. Scientific Reports. 13
2023. The association between genetically elevated polyunsaturated fatty acids and risk of cancer. eBioMedicine. 91
2023. Not all exons are protein coding: Addressing a common misconception. Cell Genomics. 3(4)
2023. Investigating the association between diet and infection with Trichomonas gallinae in the European turtle dove (Streptopelia turtur). Environmental DNA.
2023. Exposure of wild Caspian seals (Pusa caspica) to parasites, bacterial and viral pathogens, evaluated via molecular and serological assays. Frontiers in Marine Science. 10
2023. Non-Alcoholic Fatty Liver Disease and Vitamin D in the UK Biobank: A Two-Sample Bidirectional Mendelian Randomisation Study. Nutrients. 15(6)
2023. MicroRNAs emerging coordinate with placental mammals alter pathways in endometrial epithelia important for endometrial function. iScience. 26(4)
2023. PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Communications Biology. 6
2023. Cytokine receptor IL27RA is an NF-kB-responsive gene involved in CD38 upregulation in multiple myeloma. Blood Advances.
2023. Myocarditis and coronavirus disease 2019 vaccination: A systematic review and meta-summary of cases. Biomolecules and Biomedicine.
2023. Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers. Movement Disorders.
2023. Transcellular chaperone signaling is an intercellular stress-response distinct from the HSF-1–mediated heat shock response. PLOS Biology Jakob UH (eds.). 21(2)
2023. Sampling from commercial vessel routes can capture marine biodiversity distributions effectively. Ecology and Evolution. 13(2)
2023. Honeybee queen mandibular pheromone induces a starvation response in Drosophila melanogaster. Insect Biochemistry and Molecular Biology. 154
2023. Somatostatin Receptor PET/MR Imaging of Inflammation in Patients With Large Vessel Vasculitis and Atherosclerosis. Journal of the American College of Cardiology. 81(4), pp. 336-354
2023. GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data. Neuro-Oncology.
2023. Ergothioneine: an underrecognised dietary micronutrient required for healthy ageing?. British Journal of Nutrition. 129(1), pp. 104-114
2023. A fluorescent photoaffinity probe for formyl peptide receptor 1 labelling in living cells. RSC Chemical Biology. 216-222 4.3
2023. The New Era of High-Throughput Nanoelectrochemistry. Analytical Chemistry. 319-356 95.1
2023. Graded spikes differentially signal neurotransmitter input in cerebrospinal fluid contacting neurons of the mouse spinal cord. iScience. 26(1)
2023. Nitric oxide synthase phosphorylation in fetoplacental endothelium is enhanced by agonism of Piezo1 mechanosensor in small for gestational age babies. Reproduction & Fertility. 4(1)
2023. Phylogenetic analyses reveal bat communities in Northwestern Mexico harbour a high diversity of novel cryptic ectoparasite species. Ecology and Evolution. 13(2)
2023. Sex-bias in utero alters ovarian reserve but not uterine capacity in female offspring. Biology of Reproduction. 108(2), pp. 304-315
2023. GABAergic regulation of cell proliferation within 1 the adult mouse spinal cord. Neuropharmacology. 223
2023. Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type diffuse large B-cell lymphoma. Blood Advances. 7(5), pp. 845-855
2023. Guideline-directed medical therapy is similarly effective in heart failure with mildly reduced ejection fraction. Clinical Research in Cardiology. 112(1), pp. 111-122
2023. Mechanistic Study of the Conductance and Enhanced Single-Molecule Detection in a Polymer–Electrolyte Nanopore. ACS Nanoscience Au.
2023. Effect of Red-Beetroot-Supplemented Diet on Gut Microbiota Composition and Metabolite Profile of Weaned Pigs—A Pilot Study. Animals. 13(13)
2023. Mass Spectrometry Reveals that Oxysterols are Secreted from Non-Alcoholic Fatty Liver Disease Induced Organoids. The Journal of Steroid Biochemistry and Molecular Biology. 232
2023. Relationship among diabetes, obesity and cardiovascular disease phenotypes: a UK Biobank cohort study. Diabetes Care.
2023. Regulation of microRNA expression by the adaptor protein GRB2. Scientific Reports. 13
2023. m6A Regulates the Stability of Cellular Transcripts Required for Efficient KSHV Lytic Replication. Viruses. 15(6)
2023. Stakeholder consensus suggest strategies to promote sustainability in an artisanal fishery with high rates of poaching and marine mammal bycatch. People and Nature.
2023. Metagenomics Data Visualization Using R. , pp. 359-392
2023. Spontaneous EBV-Reactivation during B Cell Differentiation as a Model for Polymorphic EBV-Driven Lymphoproliferation. Cancers. 3083-3083 15.12
2023. Are PIEZO1 channels a potential therapeutic target for heart failure? Getting to the heart of the matter. Expert Opinion on Therapeutic Targets. , pp. 1-3
2023. Transcriptional response of endometrial cells to insulin, cultured using microfluidics. Reproduction and Fertility. 4(2)
2023. Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system. Lab on a Chip.
2023. GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19. Nature. 617, pp. 764-768
2023. The SHDRA syndrome-associated gene
2023. The in-tissue molecular architecture of β-amyloid pathology in the mammalian brain. Nature Communications.
2023. Differential Efficacy From the Addition of Bortezomib to R-CHOP in Diffuse Large B-Cell Lymphoma According to the Molecular Subgroup in the REMoDL-B Study With a 5-Year Follow-Up. Journal of Clinical Oncology. 41(15), pp. 2718-2723
2023. Clinical characteristics, management, and outcomes of pulmonary valve myxoma: systematic review of published case reports. World Journal of Surgical Oncology. 21(1)
2023. One genome, multiple phenotypes: decoding the evolution and mechanisms of environmentally induced developmental plasticity in insects. Biochemical Society Transactions. 51(2), pp. 675-689
2023. Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions. JNCI: Journal of the National Cancer Institute. 115(6), pp. 712-732
2023. Catalase: A critical node in the regulation of cell fate. Free Radical Biology and Medicine. 56-66 199
2023. Kaposi’s sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs. Nature Communications. 14
2023. Inhibition of Chikungunya virus genome replication by targeting essential RNA structures within the virus genome. Antiviral Research. 211
2023. Stress‐induced F‐Box protein‐coding gene OsFBX257 modulates drought stress adaptations and ABA responses in rice. Plant, Cell & Environment. 46(4), pp. 1207-1231
2023. Piezo1 channel-mediated Ca2+ signalling inhibits LPS-induced activation of the NF-κB inflammatory signalling pathway and generation of TNF-α and IL-6 in microglial cells. Glia. 71(4), pp. 848-865
2022. Five-Year Survival Results from the Remodl-B Trial (ISRCTN 51837425) Show Improved Outcomes in Diffuse Large B-Cell Lymphoma Molecular Subgroups from the Addition of Bortezomib to R-CHOP Chemoimmunotherapy. Blood. 140(Supplement 1), pp. 1770-1772
2022. HERPESVIRUSES OF THE CASPIAN SEALS (PUSA CASPICA). МИКРОБИОЛОГИЯ ЖӘНЕ ВИРУСОЛОГИЯ. (2(37))
2022. Putting nutrition education on the table: development of a curriculum to meet future doctors’ needs. BMJ Nutrition, Prevention & Health. 208-216 5.2
2022. Treating glioblastoma often makes a MES. Nature Cancer. 3(12), pp. 1446-1448
2022. Population-based analysis of POT1 variants in a cutaneous melanoma case–control cohort. Journal of Medical Genetics (JMG).
2022. Correction: Advanced care planning during the COVID-19 pandemic: ceiling of care decisions and their implications for observational data. BMC Palliative Care. 21(1)
2022. High levels of HDAC expression correlate with microglial aging. Expert Opinion on Therapeutic Targets. , pp. 911-922
2022. 2nd Nutrition and Cancer Networking Meeting Nutrition and Breast Cancer: Translating Evidence into Practice. Proceedings of the Nutrition Society.
2022. Evidence for strain-specific virulence of Trichomonas gallinae in African columbiformes. Parasitology (Cambridge).
2022. Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity. American Journal of Human Genetics. 109(12), pp. 2210-2229
2022. From mesenchymal niches to engineered in vitro model systems: Exploring and exploiting biomechanical regulation of vertebrate hedgehog signalling. Materials Today Bio. 17
2022. Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1. British Journal of Pharmacology.
2022. Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features. Nature Genetics. 54(11), pp. 1675-1689
2022. Memory of social experience affects female fecundity via perception of fly deposits. BMC Biology. 20
2022. Probing RNA Conformations Using a Polymer–Electrolyte Solid-State Nanopore. ACS Nano. 16(12), pp. 20075-20085
2022. In the context of the triple burden of malnutrition: A systematic review of gene-diet interactions and nutritional status. Critical Reviews in Food Science and Nutrition.
2022. Pseudomonas aeruginosa utilises the host-derived polyamine spermidine to facilitate antimicrobial tolerance.. JCI Insight. 7.22
2022. Orai1 Inhibitors as Potential Treatments for Pulmonary Arterial Hypertension. Circulation Research. 131(9), pp. e102-e119
2022. Putting nutrition education on the table: development of a curriculum to meet future doctors’ needs. British Journal of Nutrition.
2022. Biological Effects of Modifications of the Englerin A Glycolate. ACS Medicinal Chemistry Letters. 13(9), pp. 1472-1476
2022. Maternal Cardiac Changes in Women With Obesity and Gestational Diabetes Mellitus.. Diabetes Care.
2022. APRIL Drives a Coordinated but Diverse Response as a Foundation for Plasma Cell Longevity. The Journal of Immunology. 926-937 209.5
2022. Higher polygenic risk for melanoma is associated with improved survival in a high ultraviolet radiation setting. Journal of Translational Medicine. 20(1)
2022. Differences in the management of patients requiring an emergency resection for colonic cancer in two European populations. BJS Open. 6(5)
2022. Model averaging in calibration of near-infrared instruments with correlated high-dimensional data. Journal of Applied Statistics.
2022. Nanopore fingerprinting of supramolecular DNA nanostructures. Biophysical Journal. 4882-4891 121.24
2022. Long overdue: undergraduate nutrition education for medical students. British Journal of Nutrition.
2022. Investigation of the association between high arachidonic acid synthesis and colorectal polyp incidence within a generally healthy UK population: a Mendelian randomisation approach. Lifestyle Genomics. 107-110 15
2022. Positive strand RNA viruses differ in the constraints they place on the folding of their negative strand.. RNA.
2022. A Feature-subspace-based Ensemble Method for
2022. Environmentally Responsive Reproduction: Neuroendocrine Signalling and the Evolution of Eusociality. Current Opinion in Insect Science. 53
2022. Genomic and microenvironmental landscape of stage I follicular lymphoma, compared with stage III/IV. Blood Advances. 5482-5493 6.18
2022. Reduction of heart failure guideline‐directed medication during hospitalization: prevalence, risk factors, and outcomes. ESC Heart Failure. 9(5), pp. 3298-3307
2022. Atrial fibrillation and risk of progressive heart failure in patients with preserved ejection fraction heart failure. ESC Heart Failure. 9(5), pp. 3254-3263
2022. Coexistent Diabetes Is Associated With the Presence of Adverse Phenotypic Features in Patients With Hypertrophic Cardiomyopathy. Diabetes Care. 45(8), pp. 1852-1862
2022. Interplay between demographic, clinical and polygenic risk factors for severe COVID-19. International Journal of Epidemiology. 51(5), pp. 1384-1395
2022. Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity. Adipocyte. 11(1), pp. 366-378
2022. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia. 1720-1748 36.7
2022. A new integrated assessment framework for climate-smart nutrition security in sub-Saharan Africa: the integrated Future Estimator for Emissions and Diets (iFEED). Frontiers in Sustainable Food Systems. 6
2022. Standardized annotation of translated open reading frames. Nature Biotechnology. 40, pp. 994-999
2022. Uncovering the burden of hidden ciliopathies in the 100 000 Genomes Project: a reverse phenotyping approach. Journal of Medical Genetics. 59(12), pp. 1151-1164
2022. Associations between liver X receptor polymorphisms and blood lipids: a systematic review and meta-analysis. Steroids.
2022. SpheroidAnalyseR—an online platform for analyzing data from 3D spheroids or organoids grown in 96-well plates. Journal of Biological Methods. 9(4)
2022. Antibiotics made to order. Science. 376(6596), pp. 919-920
2022. Glioma progression is shaped by genetic evolution and microenvironment interactions.. Cell. 185(12), pp. 2184-2199
2022. Investigating the structural changes due to adenosine methylation of the Kaposi’s sarcoma-associated herpes virus ORF50 transcript. PLoS Computational Biology. 18(5)
2022. Novel SIX6 mutations cause recessively inherited congenital cataract, microcornea, and corneal opacification with or without coloboma and microphthalmia. Molecular Vision. 28, pp. 57-69
2022. The development of an unsupervised hierarchical clustering analysis of dual-polarization weather surveillance radar observations to assess nocturnal insect abundance and diversity. Remote Sensing in Ecology and Conservation. 8(5), pp. 698-716
2022. Differential Effects of Dietary versus Exercise Intervention on Intrahepatic MAIT Cells and Histological Features of NAFLD. Nutrients. 14.11
2022. MicroRNA-resistant alleles of HOMEOBOX DOMAIN-2 modify inflorescence branching and increase grain protein content of wheat. Science Advances. 8(19)
2022. Systemic inflammation is associated with future risk of fatal infection: an observational cohort study. The Journal of Infectious Diseases.
2022. The COLO-COHORT (Colorectal Cancer Cohort) study: Protocol for a multi-centre, observational research study and development of a consent-for-contact research platform. Colorectal Disease. 24(10), pp. 1216-1226
2022. Blocking of NF-kB/p38 MAPK pathways mitigates oligodendrocyte pathology in a model of neonatal white matter injury. ACTA NEUROBIOLOGIAE EXPERIMENTALIS. 82(1), pp. 52-64
2022. Successful storage of Trichomonas gallinae on Whatman FTA cards following culture. Conservation Genetics Resources. 14(2), pp. 225-229
2022. Unique Metabolic Profiles Associate with Gestational Diabetes and Ethnicity in Low- and High-Risk Women Living in the UK. The Journal of Nutrition. 152(10), pp. 2186-2197
2022. Plastic responses of males and females interact to determine mating behavior. Evolution. 76(9), pp. 2116-2129
2022. Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice. Cells. 11(7)
2022. ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinomycetes. Microbial Genomics. 8(7)
2022. Molecular subclusters of follicular lymphoma: a report from the United Kingdom’s Haematological Malignancy Research Network. Blood Advances. 5716-5731 6.21
2022. Simulation of the Radar Cross Section of a Noctuid Moth. Remote Sensing. 14(6)
2022. Noggin proteins are multifunctional extracellular regulators of cell signalling. Genetics.
2022. Ethnic-specific associations between dietary consumption and gestational diabetes mellitus incidence: A meta-analysis. PLOS Global Public Health. 2(5)
2022. Defining novel causal SNPs and linked phenotypes at melanoma-associated loci. Human Molecular Genetics. 31(17), pp. 2845-2856
2022. Coronary microvascular function and visceral adiposity in patients with normal body weight and type 2 diabetes. Obesity. 30(5), pp. 1079-1090
2022. COVID-19, childhood obesity, and NAFLD: colliding pandemics. The Lancet Gastroenterology and Hepatology. 499-501 7.6
2022. Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient-induced pluripotent stem cell-derived retinal pigment epithelium cells. Clinical and Translational Medicine. 12(3)
2022. Unlocking the potential of the UK 100,000 Genomes Project—lessons learned from analysis of the “Congenital Malformations caused by Ciliopathies” cohort. American Journal of Medical Genetics Part C: Seminars in Medical Genetics. 190(1), pp. 5-8
2022. Fieldwork Challenges Stemming from Doing Studies in Illegal Wildlife Trade (IWT). Journal of Economic Sociology. 23(1), pp. 125-153
2022. Cereal Architecture and Its Manipulation. Annual Plant Reviews Online. 5(1)
2022. Structural analysis of 3’UTRs in insect flaviviruses reveals novel determinants of sfRNA biogenesis and provides new insights into flavivirus evolution. Nature Communications. 13(1)
2022. Online Pre-Order Systems for School Lunches: Insights from a Cross-Sectional Study in Primary Schools. Nutrients. 14.5
2022. Orthopaedic Aspects of SAMS Syndrome.. Journal of Pediatric Genetics. 11(1), pp. 51-58
2022. Assessing rates of parasite coinfection and spatiotemporal strain variation via metabarcoding: insights for the conservation of European Turtle Doves Streptopelia turtur. Molecular Ecology. 31(9), pp. 2730-2751
2022. Sparse modelling of cancer patients’ survival based on genomic copy number alterations. Journal of Biomedical Informatics. 128
2022. Dysregulation of the miR-30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication. EMBO Reports. 23(5)
2022. Missense mutation of MAL causes a rare leukodystrophy similar to Pelizaeus-Merzbacher disease. European Journal of Human Genetics. 30(7), pp. 860-864
2022. Female fruit flies cannot protect stored sperm from high temperature damage. Journal of Thermal Biology. 105
2022. An ex vivo perfused ventilated murine lung model suggests lack of acute pulmonary toxicity of the potential novel anticancer agent (−)-englerin A. Archives of Toxicology. 96(4), pp. 1055-1063
2022. A subcellular cookie cutter for spatial genomics in human tissue. Analytical and Bioanalytical Chemistry. 5483-5492 414.18
2022. Genomic signatures of recent adaptation in a wild bumblebee.. Molecular Biology and Evolution. 39(2)
2022. Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1. eLife. 11
2022. Prospective Longitudinal Characterization of the Relationship between Diabetes and Cardiac Structural and Functional Changes. Cardiology Research and Practice. 2022
2022. RNA-Seq analysis of a Pax3-expressing myoblast clone in-vitro and effect of culture surface stiffness on differentiation. Scientific Reports. 12(1)
2022. A Feasibility Study Exploring Measures of Autonomic Function in Patients With Failed Back Surgery Syndrome Undergoing Spinal Cord Stimulation. Neuromodulation: Technology at the Neural Interface.
2022. Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation. Health Technology Assessment. 26(4), pp. 1-128
2022. Origin and expansion of the world's most widespread pinniped: range-wide population genomics of the harbour seal (Phoca vitulina).. Molecular ecology. 31(6), pp. 1682-1699
2022. Phenotypic Plasticity: What Has DNA Methylation Got to Do with It?. Insects. 13(2)
2022. Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity. The Journal of clinical investigation.
2022. PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice and Fruit Flies. Biological Psychiatry. 92(4), pp. 323-334
2022. Non-selective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903. Journal of Biological Chemistry. 298(2)
2022. Interpreting ciliopathy-associated missense variants of uncertain significance (VUS) in Caenorhabditis elegans. Human Molecular Genetics. 31(10), pp. 1574-1587
2022. Kv3 channels contribute to the excitability of sub-populations of spinal cord neurons in lamina VII. eNeuro.
2022. Diabetes mellitus and the causes of hospitalisation in people with heart failure. Diabetes and Vascular Disease Research. 19(1), pp. 1-7
2022. Hypoxia signalling in the regulation of innate immune training. Biochemical Society Transactions. 50(1), pp. 413-422
2022. Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts. British Journal of Dermatology. 186(5), pp. 823-834
2022. Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma.. The Journal of investigative dermatology. 142(8), pp. 1607-1616
2022. A System for In Vitro Generation of Mature Murine Plasma Cells Uncovers Differential Blimp-1/Prdm1 Promoter Usage. Journal of Immunology. 514-525 208.2
2022. Development of a multiplex microsatellite marker set for the study of the solitary red mason bee, Osmia bicornis (Megachilidae). Molecular Biology Reports. 49(1), pp. 783-788
2022. Combination therapies for COVID‐19: An overview of the clinical trials landscape. British Journal of Clinical Pharmacology. 88(4), pp. 1590-1597
2022. Molecular diagnoses in the congenital malformations caused by ciliopathies cohort of the 100,000 Genomes Project. Journal of Medical Genetics. 59(8), pp. 737-747
2022. Pharmacology of TRPC Channels and Its Potential in Cardiovascular and Metabolic Medicine. Annual Review of Pharmacology and Toxicology. 62, pp. 427-446
2022. Pharmacologic and genetic inhibition of cholesterol esterification enzymes reduces tumour burden: a systematic review and meta-analysis of preclinical models. Biochemical pharmacology. 196
2022. Early-life seasonal, weather and social effects on telomere length in a wild mammal. Molecular Ecology. 31(23), pp. 5993-6007
2022. The N-terminal substrate specificity of the SurE peptide cyclase. Organic and Biomolecular Chemistry. 20(36), pp. 7232-7235
2022. Speed vernalization to accelerate generation advance in winter cereal crops. Molecular Plant.
2021. Atlas of receptor genes expressed by the bovine morula and corresponding ligand‐related genes expressed by uterine endometrium. Molecular Reproduction and Development. 88(10), pp. 694-704
2021. Conceptus-modulated innate immune function during early pregnancy in ruminants: a review. Animal Reproduction. 18(1)
2021. Genetic Relationship Between Endometriosis and Melanoma. Frontiers in Reproductive Health. 3
2021. USE OF SHARED GAMMA FRAILTY MODEL IN ANALYSIS OF SURVIVAL DATA IN TWINS. THEORETICAL BIOLOGY FORUM. 114(1), pp. 45-58
2021. NAFLD and Vitamin D: Evidence for Intersection of MicroRNA Regulated Pathways. Nutrition Research Reviews.
2021. Fine-scale population structure and demographic history of British Pakistanis. Nature Communications. 12(1)
2021. Personalised reprogramming to prevent progressive pacemaker-related left ventricular dysfunction: A phase II randomised, controlled clinical trial. PLoS ONE. 16(12)
2021. Optimization of ribosome footprinting conditions for Ribo-Seq in human and Drosophila melanogaster tissue culture cells. Frontiers in Molecular Biosciences.
2021. Choosing drugs for UK COVID-19 treatment trials. Nature Reviews Drug Discovery.
2021. Plastic responses of survival and fertility following heat stress in pupal and adult Drosophila virilis. Ecology and Evolution. 11(24), pp. 18238-18247
2021. An Overview of Strategies for Detecting Genotype-Phenotype Associations Across Ancestrally Diverse Populations. Frontiers in Genetics. 12
2021. MiR-195 and Its Target SEMA6D Regulate Chemoresponse in Breast Cancer. Cancers. 13(23)
2021. Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data. Nature Communications. 12(1)
2021. The Roles of Temperature-Related Post-Transcriptional Regulation in Cereal Floral Development. Plants. 10(11)
2021. Inhibition of ionotropic GluR signaling preserves oligodendrocyte lineage and myelination in an ex vivo rat model of white matter ischemic injury. Acta Neurobiologiae Experimentalis. 81(3), pp. 233-248
2021. Ergothioneine supplementation in people with metabolic syndrome (ErgMS): protocol for a randomised, double-blind, placebo-controlled pilot study. Pilot and Feasibility Studies. 7(1)
2021. The epigenetic evolution of gliomas is determined by their IDH1 mutation status and treatment regimen.
2021. OMRT-3. Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment. Neuro-oncology advances. 3(Suppl 2), pp. ii7-ii8
2021. Characterization and prognostic value of LXR splice variants in triple-negative breast cancer. iScience. 24(10)
2021. Empagliflozin Treatment is Associated With Improvements in Cardiac Energetics and Function and Reductions in Myocardial Cellular Volume in Patients With Type 2 Diabetes. Diabetes.
2021. Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation of OBFC1. Human Molecular Genetics.
2021. Causes of death in people with cardiovascular disease: a UK Biobank cohort study. Journal of the American Heart Association. 10(22)
2021. Piggybacking on the Cholera Toxin: Identification of a CTB-binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons. Bioconjugate Chemistry. 32(10), pp. 2205-2212
2021. Influence of age on surgical treatment and postoperative outcomes of patients with colorectal cancer in Denmark and Yorkshire, England. Colorectal Disease. 23(12), pp. 3152-3161
2021. Pericyte insulin receptors modulate retinal vascular remodeling and endothelial angiopoietin signaling. Endocrinology.
2021. A modified intron of VRT2 drives glume and grain elongation in wheat. Molecular Plant. 14(9), pp. 1421-1423
2021. Insights into the Evolving Roles of Circular RNAs in Cancer. Cancers. 13(16)
2021. Ferries and Environmental DNA: Underway Sampling From Commercial Vessels Provides New Opportunities for Systematic Genetic Surveys of Marine Biodiversity. Frontiers in Marine Science. 8
2021. Social environment drives sex and age-specific variation in Drosophila melanogaster microbiome composition and predicted function. Molecular Ecology. 30(22), pp. 5831-5843
2021. Novel Paracrine Action of Endothelium enhances Glucose Uptake in Muscle and Fat. Circulation Research.
2021. Asymmetric expansions of FT and TFL1 lineages characterize differential evolution of the EuPEBP family in the major angiosperm lineages. BMC Biology. 19
2021. Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment.
2021. Pre-mRNA Processing Factors and Retinitis Pigmentosa: RNA Splicing and Beyond. Frontiers in Cell and Developmental Biology. 9
2021. Arabidopsis Coexpression Tool: a tool for gene coexpression analysis in Arabidopsis thaliana. iScience. 24(8)
2021. A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR. American journal of human genetics. 108(9), pp. 1611-1630
2021. Evolution and genomic organization of the insect sHSP gene cluster and coordinate regulation in phenotypic plasticity. Ecology and Evolution. 21
2021. Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals. HGG advances. 2(3)
2021. Dietary copper and selenium are associated with insulin resistance in overweight and obese Malaysian adults. Nutrition Research. 93, pp. 38-49
2021. Infection and Adverse Outcomes in People With Chronic Heart Failure. Journal of the American College of Cardiology. 78(7), pp. 760-760
2021. Data analysis workflow for the detection of canine vector-borne pathogens using 16 S rRNA Next-Generation Sequencing. BMC Veterinary Research. 17
2021. Auxin in Root Development.. Cold Spring Harbor perspectives in biology. 13(8)
2021. Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms.. American Journal of Human Genetics (AJHG). 108(9), pp. 1631-1646
2021. Trehalose-Induced Remodelling of the Human Microbiota Affects Clostridioides difficile Infection Outcome in an In Vitro Colonic Model: A Pilot Study. Frontiers in Cellular and Infection Microbiology. 11
2021. Dietary carbohydrates and fats in nonalcoholic fatty liver disease. Nature Reviews Gastroenterology & Hepatology. 770-786 18
2021. Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching. Nucleic Acids Research.
2021. Cytoplasmic long non-coding RNAs are differentially regulated and translated during human neuronal differentiation. RNA.
2021. APRIL drives a co-ordinated but diverse response as a foundation for plasma cell longevity.
2021. Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi. Proceedings of the National Academy of Sciences. 118(27)
2021. Impact of QRS duration on left ventricular remodelling and survival in patients with heart failure. Journal of Cardiovascular Medicine. 22(11), pp. 848-856
2021. How plants get round problems: new insights into the root obstacle avoidance response. New Phytologist. 231(1), pp. 8-10
2021. Transcriptome profiles of stem-like cells from primary breast cancers allow identification of ITGA7 as a predictive marker of chemotherapy response. British Journal of Cancer. 125, pp. 983-993
2021. Suboptimal Dosing of β-Blockers in Chronic Heart Failure: A Missed Opportunity?. Journal of Cardiovascular Nursing.
2021. Temperatures that sterilize males better match global species distributions than lethal temperatures. Nature Climate Change. 11(6), pp. 481-484
2021. Luminal Bioavailability of Orally Administered ω-3 PUFAs in the Distal Small Intestine, and Associated Changes to the Ileal Microbiome, in Humans with a Temporary Ileostomy. The Journal of nutrition.
2021. Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis. Endocrinology. 162(8)
2021. In silico identification of glycosylphosphatidylinositol-anchored proteins in Paracoccidioides spp.. Future Microbiology. 16(8), pp. 589-606
2021. Protein acetylation in the critical biological processes in protozoan parasites. Trends in Parasitology. 37(9), pp. 815-830
2021. A standalone β-ketoreductase acts concomitantly with biosynthesis of the antimycin scaffold. ACS Chemical Biology. 16(7), pp. 1152-1158
2021. Endothelial IGF‐1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity. EMBO Reports. 22(5)
2021. International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020). Frontiers in Human Neuroscience. 14
2021. Efficient infection of organotypic hippocampal slice cultures with adenovirus carrying the transgene REST/NRSF. Journal of Neuroscience Methods. 356
2021. The functions of repressor element 1-silencing transcription factor in models of epileptogenesis and post-ischemia. Metabolic Brain Disease. 36, pp. 1135-1150
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2019. Emerging concepts of shear stress in placental development and function.. Molecular Human Reproduction. 25(6), pp. 329-339
2019. Gene-expression profiling of bortezomib added to standard chemoimmunotherapy for diffuse large B-cell lymphoma (REMoDL-B): an open-label, randomised, phase 3 trial. The Lancet Oncology. 20(5), pp. 649-662
2019. Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome.. Genome biology. 20(1), pp. 64-64
2019. Exposure to males, but not receipt of sex peptide, accelerates functional aging in female fruit flies. Functional Ecology. 33(8), pp. 1459-1468
2019. Integrated Approaches to Studying Male and Female Thermal Fertility Limits. Trends in Ecology and Evolution. 34(6), pp. 492-493
2019. Doomed from the TERT? A Two-Stage Model of Tumorigenesis in IDH-Wild-Type Glioblastoma. Cancer Cell. 35(4), pp. 542-544
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2019. Ibrutinib induces chromatin reorganisation of chronic lymphocytic leukaemia cells. Oncogenesis. 8
2019. Getting energy balance right in an obesogenic world. Proceedings of the Nutrition Society. 259-261 78.3
2019. Letter to the Editor: A response to Selvaraj and Boisclair (2019). Journal of Dairy Science. 102(4), pp. 2826-2827
2019. Pinstatic Acid Promotes Auxin Transport by Inhibiting PIN Internalization. Plant Physiology. 180(2), pp. 1152-1165
2019. Ortholog of the polymerase theta helicase domain modulates DNA replication in Trypanosoma cruzi. Scientific Reports. 9
2019. Comparative transcriptomics in Leishmania braziliensis: disclosing differential gene expression of coding and putative noncoding RNAs across developmental stages. RNA Biology. 16(5), pp. 639-660
2019. The ciliary Frizzled-like receptor Tmem67 regulates canonical Wnt/β-catenin signalling in the developing cerebellum via Hoxb5. Scientific Reports. 9
2019. Selective auxin agonists induce specific AUX/IAA protein degradation to modulate plant development.. Proceedings of the National Academy of Sciences of the United States of America. 116(13), pp. 6463-6472
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2019. From genes to environment in shaping of an embryo: understanding embryonic-extraembryonic interactions at the BSDB autumn meeting in Oxford. Development Genes and Evolution. 229(2-3), pp. 83-87
2019. From sugar to liver fat and public health: Systems biology driven studies in understanding non-alcoholic fatty liver disease pathogenesis. Proceedings of the Nutrition Society. 290-304 78.3