Publications
Selected LeedsOmics-related publications
2022. Reduction of heart failure guideline‐directed medication during hospitalization: prevalence, risk factors, and outcomes. ESC Heart Failure. 
2022. Atrial fibrillation and risk of progressive heart failure in patients with preserved ejection fraction heart failure. ESC Heart Failure. 
2022. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia. 1720-1748 36.7
2022. Guideline-directed medical therapy is similarly effective in heart failure with mildly reduced ejection fraction. Clinical Research in Cardiology.
2022. Uncovering the burden of hidden ciliopathies in the 100,000 Genomes Project: a reverse phenotyping approach. Journal of Medical Genetics.
2022. Glioma progression is shaped by genetic evolution and microenvironment interactions.. Cell.
2022. Novel SIX6 mutations cause recessively inherited congenital cataract, microcornea, and corneal opacification with or without coloboma and microphthalmia. Molecular Vision. 28, pp. 57-69
2022. The development of an unsupervised hierarchical clustering analysis of dual-polarization weather surveillance radar observations to assess nocturnal insect abundance and diversity. Remote Sensing in Ecology and Conservation.
2022. Differential Effects of Dietary versus Exercise Intervention on Intrahepatic MAIT Cells and Histological Features of NAFLD. Nutrients. 14.11
2022. MicroRNA-resistant alleles of HOMEOBOX DOMAIN-2 modify inflorescence branching and increase grain protein content of wheat. Science Advances. 8(19)
2022. Systemic inflammation is associated with future risk of fatal infection: an observational cohort study. The Journal of Infectious Diseases.
2022. ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinomycetes. Microbial Genomics.
2022. Molecular subclusters of follicular lymphoma: a report from the UK's Haematological Malignancy Research Network. Blood Advances.
2022. Simulation of the Radar Cross Section of a Noctuid Moth. Remote Sensing. 14(6)
2022. Noggin proteins are multifunctional extracellular regulators of cell signalling. Genetics.
2022. Ethnic-specific associations between dietary consumption and gestational diabetes mellitus incidence: A meta-analysis. PLOS Global Public Health. 2.5
2022. Defining novel causal SNPs and linked phenotypes at melanoma-associated loci. Human Molecular Genetics.
2022. Coronary microvascular function and visceral adiposity in patients with normal body weight and type 2 diabetes. Obesity. 30(5), pp. 1079-1090
2022. COVID-19, childhood obesity and NAFLD: Colliding pandemics. The Lancet Gastroenterology and Hepatology.
2022. Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient-induced pluripotent stem cell-derived retinal pigment epithelium cells. Clinical and Translational Medicine. 12(3)
2022. Unlocking the potential of the UK 100,000 Genomes Project—lessons learned from analysis of the “Congenital Malformations caused by Ciliopathies” cohort. American Journal of Medical Genetics Part C: Seminars in Medical Genetics. 190(1), pp. 5-8
2022. Fieldwork Challenges Stemming from Doing Studies in Illegal Wildlife Trade (IWT). Journal of Economic Sociology. 23(1), pp. 125-153
2022. Cereal Architecture and Its Manipulation. Annual Plant Reviews Online. 5(1)
2022. Online Pre-Order Systems for School Lunches: Insights from a Cross-Sectional Study in Primary Schools. Nutrients. 14.5
2022. Orthopaedic Aspects of SAMS Syndrome.. Journal of Pediatric Genetics. 11(1), pp. 51-58
2022. Assessing rates of parasite coinfection and spatiotemporal strain variation via metabarcoding: insights for the conservation of European Turtle Doves Streptopelia turtur. Molecular Ecology.
2022. Dysregulation of the miR-30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication. EMBO Reports.
2022. Missense mutation of MAL causes a rare leukodystrophy similar to Pelizaeus-Merzbacher disease. European Journal of Human Genetics.
2022. Female fruit flies cannot protect stored sperm from high temperature damage. Journal of Thermal Biology. 105
2022. An ex vivo perfused ventilated murine lung model suggests lack of acute pulmonary toxicity of the potential novel anticancer agent (−)-englerin A. Archives of Toxicology. 96(4), pp. 1055-1063
2022. Genomic signatures of recent adaptation in a wild bumblebee.. Molecular Biology and Evolution. 39(2)
2022. Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1. eLife. 11
2022. Prospective Longitudinal Characterization of the Relationship between Diabetes and Cardiac Structural and Functional Changes. Cardiology Research and Practice. 2022
2022. A Feasibility Study Exploring Measures of Autonomic Function in Patients With Failed Back Surgery Syndrome Undergoing Spinal Cord Stimulation. Neuromodulation: Technology at the Neural Interface.
2022. Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation. Health Technology Assessment. 26(4), pp. 1-128
2022. Origin and expansion of the world's most widespread pinniped: range-wide population genomics of the harbour seal (Phoca vitulina).. Molecular ecology.
2022. Phenotypic Plasticity: What Has DNA Methylation Got to Do with It?. Insects. 13(2)
2022. CLAVATA
2022. Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity. The Journal of clinical investigation.
2022. PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice and Fruit Flies. Biological Psychiatry.
2022. Non-selective TRPC channel inhibition and suppression of aminoglycoside-induced premature termination codon readthrough by the small molecule AC1903. Journal of Biological Chemistry. 298(2)
2022. Diabetes mellitus and the causes of hospitalisation in people with heart failure. Diabetes and Vascular Disease Research. 19(1), pp. 1-7
2022. Hypoxia signalling in the regulation of innate immune training. Biochemical Society Transactions. 50(1), pp. 413-422
2022. Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts. British Journal of Dermatology. 186(5), pp. 823-834
2022. Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma.. The Journal of investigative dermatology. 142(8), pp. 1607-1616
2022. A System for In Vitro Generation of Mature Murine Plasma Cells Uncovers Differential Blimp-1/Prdm1 Promoter Usage. Journal of Immunology. 514-525 208.2
2022. Development of a multiplex microsatellite marker set for the study of the solitary red mason bee, Osmia bicornis (Megachilidae). Molecular Biology Reports. 49(1), pp. 783-788
2022. Molecular diagnoses in the congenital malformations caused by ciliopathies cohort of the 100,000 Genomes Project. Journal of Medical Genetics. 59(8), pp. 737-747
2022. Pharmacology of TRPC Channels and Its Potential in Cardiovascular and Metabolic Medicine. Annual Review of Pharmacology and Toxicology. 62, pp. 427-446
2022. Pharmacologic and genetic inhibition of cholesterol esterification enzymes reduces tumour burden: a systematic review and meta-analysis of preclinical models. Biochemical pharmacology. 196
2022. Standardized annotation of translated open reading frames. Nature Biotechnology.
2022. Environmentally Responsive Reproduction: Neuroendocrine Signalling and the Evolution of Eusociality. Current Opinion in Insect Science. , pp. 100951-100951
2022. Genomic and microenvironmental landscape of stage I follicular lymphoma, compared to stage III/IV.. Blood advances. bloodadvances.2022008355+
2022. Interplay between demographic, clinical and polygenic risk factors for severe COVID-19. International Journal of Epidemiology.
2022. Speed vernalization to accelerate generation advance in winter cereal crops. Molecular Plant.
2022. Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity. Adipocyte. 11(1), pp. 366-378
2022. A new integrated assessment framework for climate-smart nutrition security in sub-Saharan Africa: the integrated Future Estimator for Emissions and Diets (iFEED). Frontiers in Sustainable Food Systems.
2022. Associations between liver X receptor polymorphisms and blood lipids: a systematic review and meta-analysis. Steroids.
2022. SpheroidAnalyseR – an online platform for analysing data from 3D spheroids or organoids grown in 96-well plates. Journal of Biological Methods.
2022. Antibiotics made to order. Science. 376(6596), pp. 919-920
2022. Investigating the structural changes due to adenosine methylation of the Kaposi’s sarcoma-associated herpes virus ORF50 transcript. PLoS Computational Biology. 18(5)
2022. Plant peptidoglycan precursor biosynthesis: Conservation between moss chloroplasts and Gram-negative bacteria. Plant Physiology.
2022. Bridging the gap with the UK Genomics Pathology Imaging Collection. Nature Medicine. 28(6), pp. 1107-1108
2022. The gut as a lifespan- and proteostasis-promoting signaling tissue. Frontiers in Aging.
2022. The COLO-COHORT (Colorectal Cancer Cohort) study: Protocol for a multi-centre, observational research study and development of a consent-for-contact research platform. Colorectal Disease.
2022. Blocking of NF-kB/p38 MAPK pathways mitigates oligodendrocyte pathology in a model of neonatal white matter injury. Acta Neurobiologiae Experimentalis. 82(1)
2022. Successful storage of Trichomonas gallinae on Whatman FTA cards following culture. Conservation Genetics Resources. 14(2), pp. 225-229
2022. Plastic responses of males and females interact to determine mating behaviour. Evolution.
2022. Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice. Cells. 11(7), pp. 1199-1199
2022. Protein-conjugated microbubbles for the selective targeting of S. aureus biofilms. Biofilm. 4
2022. Structural analysis of 3’UTRs in insect flaviviruses reveals novel determinants of sfRNA biogenesis and provides new insights into flavivirus evolution. Nature Communications. 13(1)
2022. Sparse modelling of cancer patients’ survival based on genomic copy number alterations. Journal of Biomedical Informatics. 128
2022. RNA-Seq analysis of a Pax3-expressing myoblast clone in-vitro and effect of culture surface stiffness on differentiation. Scientific Reports. 12(1)
2022. Kv3 channels contribute to the excitability of sub-populations of spinal cord neurons in lamina VII. eNeuro.
2022. Combination therapies for COVID‐19: An overview of the clinical trials landscape. British Journal of Clinical Pharmacology. 88(4), pp. 1590-1597
2021. USE OF SHARED GAMMA FRAILTY MODEL IN ANALYSIS OF SURVIVAL DATA IN TWINS. THEORETICAL BIOLOGY FORUM. 114(1), pp. 45-58
2021. NAFLD and Vitamin D: Evidence for Intersection of MicroRNA Regulated Pathways. Nutrition Research Reviews.
2021. Interpreting ciliopathy-associated missense variants of uncertain significance (VUS) in Caenorhabditis elegans. Human Molecular Genetics.
2021. Fine-scale population structure and demographic history of British Pakistanis. Nature Communications. 12(1)
2021. Personalised reprogramming to prevent progressive pacemaker-related left ventricular dysfunction: A phase II randomised, controlled clinical trial. PLoS ONE. 16(12)
2021. Optimization of ribosome footprinting conditions for Ribo-Seq in human and Drosophila melanogaster tissue culture cells. Frontiers in Molecular Biosciences.
2021. Choosing drugs for UK COVID-19 treatment trials. Nature Reviews Drug Discovery.
2021. Plastic responses of survival and fertility following heat stress in pupal and adult Drosophila virilis. Ecology and Evolution. 11(24), pp. 18238-18247
2021. An Overview of Strategies for Detecting Genotype-Phenotype Associations Across Ancestrally Diverse Populations. Frontiers in Genetics. 12
2021. MiR-195 and Its Target SEMA6D Regulate Chemoresponse in Breast Cancer. Cancers. 13(23)
2021. Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data. Nature Communications. 12(1)
2021. The Roles of Temperature-Related Post-Transcriptional Regulation in Cereal Floral Development. Plants. 10(11)
2021. Inhibition of ionotropic GluR signaling preserves oligodendrocyte lineage and myelination in an ex vivo rat model of white matter ischemic injury. Acta Neurobiologiae Experimentalis. 81(3), pp. 233-248
2021. Ergothioneine supplementation in people with metabolic syndrome (ErgMS): protocol for a randomised, double-blind, placebo-controlled pilot study. Pilot and Feasibility Studies. 7(1)
2021. OMRT-3. Longitudinal analysis of diffuse glioma reveals cell state dynamics at recurrence associated with changes in genetics and the microenvironment. Neuro-oncology advances. 3(Suppl 2), pp. ii7-ii8
2021. Characterization and prognostic value of LXR splice variants in triple-negative breast cancer. iScience. 24(10)
2021. Empagliflozin Treatment is Associated With Improvements in Cardiac Energetics and Function and Reductions in Myocardial Cellular Volume in Patients With Type 2 Diabetes. Diabetes.
2021. Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation of OBFC1. Human Molecular Genetics.
2021. Causes of death in people with cardiovascular disease: a UK Biobank cohort study. Journal of the American Heart Association. 10(22)
2021. Global Proteotoxicity Caused by Human β2 Microglobulin Variants Impairs the Unfolded Protein Response in C. elegans. International Journal of Molecular Sciences. 22(19)
2021. Piggybacking on the Cholera Toxin: Identification of a CTB-binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons. Bioconjugate Chemistry. 32(10), pp. 2205-2212
2021. Influence of age on surgical treatment and postoperative outcomes of patients with colorectal cancer in Denmark and Yorkshire, England. Colorectal Disease.
2021. Pericyte insulin receptors modulate retinal vascular remodeling and endothelial angiopoietin signaling. Endocrinology.
2021. A modified intron of VRT2 drives glume and grain elongation in wheat. Molecular Plant. 14(9), pp. 1421-1423
2021. Insights into the Evolving Roles of Circular RNAs in Cancer. Cancers. 13(16)
2021. Ferries and Environmental DNA: Underway Sampling From Commercial Vessels Provides New Opportunities for Systematic Genetic Surveys of Marine Biodiversity. Frontiers in Marine Science. 8
2021. Social environment drives sex and age-specific variation in Drosophila melanogaster microbiome composition and predicted function. Molecular Ecology. 30(22), pp. 5831-5843
2021. Novel Paracrine Action of Endothelium enhances Glucose Uptake in Muscle and Fat. Circulation Research.
2021. Asymmetric expansions of FT and TFL1 lineages characterize differential evolution of the EuPEBP family in the major angiosperm lineages. BMC Biology. 19
2021. Pre-mRNA Processing Factors and Retinitis Pigmentosa: RNA Splicing and Beyond. Frontiers in Cell and Developmental Biology. 9
2021. Arabidopsis Coexpression Tool: a tool for gene coexpression analysis in Arabidopsis thaliana. iScience. 24(8)
2021. A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR. American journal of human genetics.
2021. Evolution and genomic organization of the insect sHSP gene cluster and coordinate regulation in phenotypic plasticity. Ecology and Evolution. 21
2021. Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals. HGG advances. 2(3)
2021. Dietary copper and selenium are associated with insulin resistance in overweight and obese Malaysian adults. Nutrition Research. 93, pp. 38-49
2021. Infection and Adverse Outcomes in People With Chronic Heart Failure. Journal of the American College of Cardiology. 78(7), pp. 760-760
2021. Data analysis workflow for the detection of canine vector-borne pathogens using 16 S rRNA Next-Generation Sequencing. BMC Veterinary Research. 17
2021. A minus-end directed kinesin motor directs gravitropism in Physcomitrella patens. Nature Communications. 12
2021. Auxin in Root Development.. Cold Spring Harbor perspectives in biology. 13(8)
2021. Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms.. American Journal of Human Genetics (AJHG).
2021. Trehalose-Induced Remodelling of the Human Microbiota Affects Clostridioides difficile Infection Outcome in an In Vitro Colonic Model: A Pilot Study. Frontiers in Cellular and Infection Microbiology. 11
2021. Dietary carbohydrates and fats in nonalcoholic fatty liver disease. Nature Reviews Gastroenterology & Hepatology. 770-786 18
2021. Association of DNA damage with vitamin D and hair heavy metals of obese women. Molecular and Cellular Toxicology. 17(4), pp. 429-438
2021. Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching. Nucleic Acids Research.
2021. Cytoplasmic long non-coding RNAs are differentially regulated and translated during human neuronal differentiation. RNA.
2021. Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi. Proceedings of the National Academy of Sciences.
2021. Impact of QRS duration on left ventricular remodelling and survival in patients with heart failure. Journal of Cardiovascular Medicine. 22(11), pp. 848-856
2021. How plants get round problems: new insights into the root obstacle avoidance response. New Phytologist. 231(1), pp. 8-10
2021. Early-life seasonal, weather and social effects on telomere length in a wild mammal. Molecular Ecology.
2021. Transcriptome profiles of stem-like cells from primary breast cancers allow identification of ITGA7 as a predictive marker of chemotherapy response. British Journal of Cancer. 125, pp. 983-993
2021. Suboptimal Dosing of β-Blockers in Chronic Heart Failure: A Missed Opportunity?. Journal of Cardiovascular Nursing.
2021. Temperatures that sterilize males better match global species distributions than lethal temperatures. Nature Climate Change.
2021. The 2021 FASEB Virtual Catalyst Conference on Extracellular and Organismal Proteostasis in Health and Disease, February 3‐4, 2021. The FASEB Journal. 35(6)
2021. Luminal Bioavailability of Orally Administered ω-3 PUFAs in the Distal Small Intestine, and Associated Changes to the Ileal Microbiome, in Humans with a Temporary Ileostomy. The Journal of nutrition.
2021. Endothelial insulin receptors promote VEGF-A signaling via ERK1/2 and sprouting angiogenesis. Endocrinology.
2021. In silico identification of glycosylphosphatidylinositol-anchored proteins in Paracoccidioides spp.. Future Microbiology. 16(8), pp. 589-606
2021. Protein acetylation in the critical biological processes in protozoan parasites. Trends in Parasitology. 37(9), pp. 815-830
2021. A standalone β-ketoreductase acts concomitantly with biosynthesis of the antimycin scaffold. ACS Chemical Biology. 16(7), pp. 1152-1158
2021. Endothelial IGF‐1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity. EMBO Reports. 22(5)
2021. International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020). Frontiers in Human Neuroscience. 14
2021. Efficient infection of organotypic hippocampal slice cultures with adenovirus carrying the transgene REST/NRSF. Journal of Neuroscience Methods. 356
2021. The functions of repressor element 1-silencing transcription factor in models of epileptogenesis and post-ischemia. Metabolic Brain Disease. 36, pp. 1135-1150
2021. ORAI1 Ca2+ channel as a therapeutic target in pathological vascular remodelling. Frontiers in Cell and Developmental Biology. 9
2021. Endometrium On-a-Chip Reveals Insulin- and Glucose-induced Alterations in the Transcriptome and Proteomic Secretome. Endocrinology. 162(6)
2021. Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer. Oncogene. 40, pp. 2872-2883
2021. Ribosome heterogeneity and specialization in development. WIREs RNA. 12(4)
2021. First Virtual International Congress on Cellular and Organismal Stress Responses, November 5–6, 2020. Cell Stress and Chaperones. 26(2), pp. 289-295
2021. Exploring TERRA during Leishmania major developmental cycle and continuous in vitro passages. International Journal of Biological Macromolecules. 174, pp. 573-586
2021. Modelling of full-length Piezo1 suggests importance of the proximal N-terminus for dome structure. Biophysical Journal.
2021. Molecular dynamics simulations of Piezo1 channel opening by increases in membrane tension. Biophysical Journal. 120(8), pp. P1510-P1521
2021. Placental blood flow sensing and regulation in fetal growth restriction. Placenta.
2021. New fluorescent auxin probes visualise tissue‐specific and subcellular distributions of auxin in Arabidopsis. New Phytologist. 230(2), pp. 535-549
2021. A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization. Nature Communications. 12(1)
2021. Advanced care planning during the COVID-19 pandemic: ceiling of care decisions and their implications for observational data. BMC Palliative Care. 20(1)
2021. WHSC1/NSD2 regulates immune infiltration in prostate cancer. Journal for ImmunoTherapy of Cancer. 9(2)
2021. Advances in understanding and in multi-disciplinary methodology used to assess lipid regulation of signalling cascades from the cancer cell plasma membrane. Progress in Lipid Research. 81
2021. Non-communicable disease, sociodemographic factors, and risk of death from infection: a UK Biobank observational cohort study infection death: a UK Biobank observational cohort study. The Lancet Infectious Diseases. 21(8), pp. 1184-1191
2021. Diabetes, gender and deterioration in estimated glomerular filtration rate in patients with chronic heart failure: ten-year prospective cohort study. Diabetes and Vascular Disease Research. 18(1), pp. 1-7
2021. Identification of Critical Transcriptomic Signaling Pathways in Patients with H Syndrome and Rosai-Dorfman Disease. Journal of Clinical Immunology. 41(2), pp. 441-457
2021. Comparative analysis of gene expression platforms for cell‐of‐origin classification of diffuse large B‐cell lymphoma shows high concordance. British Journal of Haematology. 192(3), pp. 599-604
2021. Friends, neighbours and enemies: an overview of the communal and social biology of plants. Plant, Cell and Environment. 44(4), pp. 997-1013
2021. Inhibition of interferon-signalling halts cancer-associated fibroblast-dependent protection of breast cancer cells from chemotherapy. British Journal of Cancer. 124, pp. 1110-1120
2021. Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 109(2), pp. 241-256
2021. Contaminations contaminate common databases. Molecular Ecology Resources. 21(2), pp. 355-362
2021. Application of the LymphGen classification tool to 928 clinically and genetically‐characterised cases of diffuse large B cell lymphoma (DLBCL). British Journal of Haematology. 216-220 192.1
2021. TMEM16A/ANO1 calcium-activated chloride channel as a novel target for the treatment of human respiratory syncytial virus infection. Thorax. 76(1), pp. 64-72
2021. Prediction of tumour pathological subtype from genomic profile using sparse logistic regression with random effects. Journal of Applied Statistics. 48(4), pp. 605-622
2021. The effect of intestinal microbiota dysbiosis on growth and detection of carbapenemase-producing Enterobacterales within an in vitro gut model. The Journal of hospital infection.
2021. Evaluation of a commercial microbial enrichment kit used prior DNA extraction to improve the molecular detection of vector-borne pathogens from naturally infected dogs. Journal of Microbiological Methods. 188, pp. 106163-106163
2020. The CEP5 Peptide Promotes Abiotic Stress Tolerance, As Revealed by Quantitative Proteomics, and Attenuates the AUX/IAA Equilibrium in Arabidopsis.. Molecular and Cellular Proteomics (MCP). 19(8), pp. 1248-1262
2020. Germline variants are associated with increased primary melanoma tumor thickness at diagnosis. Human Molecular Genetics. 29(21), pp. 3578-3587
2020. CRFK and Primary Macrophages Transcriptomes in Response to Feline Coronavirus Infection Differ Significantly. Frontiers in Genetics. 11
2020. Risk factors for melanoma by anatomical site: an evaluation of aetiological heterogeneity. British Journal of Dermatology.
2020. Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site. Communications Biology. 3(1)
2020. Primary Cilia, Ciliogenesis and the Actin Cytoskeleton: A Little Less Resorption, A Little More Actin Please. Frontiers in Cell and Developmental Biology. 8
2020. Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation. Journal of Bone and Mineral Research.
2020. Noradrenergic Signaling and Neuroinflammation Crosstalk Regulate Toxoplasma gondii-Induced Behavioral Changes. Trends in Immunology. 41(12), pp. 1072-1082
2020. Inhibition of Mitochondrial Fission and iNOS in the Dorsal Vagal Complex Protects from Overeating and Weight Gain. Molecular Metabolism.
2020. Perturbations of the gut microbiome in anti-CCP positive individuals at risk of developing rheumatoid arthritis. Rheumatology.
2020. Optimization of an Assay To Determine Colonization Resistance to Clostridioides difficile in Fecal Samples from Healthy Subjects and Those Treated with Antibiotics. Antimicrobial Agents and Chemotherapy.
2020. Estimation of environmental, genetic and parental age at conception effects on telomere length in a wild mammal. Journal of Evolutionary Biology.
2020. Association of heart failure and its comorbidities with loss of life expectancy. Heart.
2020. Drosophila melanogaster and worker honeybees (Apis mellifera) do not require olfaction to be susceptible to honeybee queen mandibular pheromone. Journal of Insect Physiology. 127
2020. A Novel, Orally Delivered Antibody Therapy and Its Potential to Prevent Clostridioides difficile Infection in Pre-clinical Models. Frontiers in Microbiology. 11
2020. Association between a 46-SNP Polygenic Risk Score and melanoma risk in Dutch patients with familial melanoma. Journal of Medical Genetics.
2020. Phytosterols and phytostanols and the hallmarks of cancer in model organisms: a systematic review and meta-analysis. Critical Reviews in Food Science and Nutrition.
2020. A recessively inherited risk locus on chromosome 13q22-31 conferring susceptibility to schizophrenia. Schizophrenia Bulletin.
2020. Dose-dependent oral glucocorticoid cardiovascular risks in people with immune-mediated inflammatory diseases: A population-based cohort study. PLoS Medicine. 17(12)
2020. Bridgehead Modifications of Englerin A Reduce TRPC4 Activity and Intravenous Toxicity but not Cell Growth Inhibition. ACS Medicinal Chemistry Letters. 11(9), pp. 1711-1716
2020. Social competition stimulates cognitive performance in a sex-specific manner. Proceedings of the Royal Society B: Biological Sciences. 287(1935)
2020. Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology. Acta Neuropathologica. 140, pp. 919-949
2020. Cryptic or silent? The known unknowns, unknown knowns and unknown unknowns of secondary metabolism. mBio. 11(5)
2020. SHOC2 scaffold protein modulates daunorubicin-induced cell death through p53 modulation in lymphoid leukemia cells. Scientific Reports. 10(1)
2020. Effect of disease-modifying agents and their association with mortality in multi-morbid patients with heart failure with reduced ejection fraction. ESC Heart Failure. 7(6), pp. 3859-3870
2020. Cross inoculation of rumen fluid to improve dry matter disappearance and its effect on bacterial composition using an in vitro batch culture model. Frontiers in Microbiology. 11
2020. Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels. Cell Reports. 33(1)
2020. Microbiota Supplementation with Bifidobacterium and Lactobacillus Modifies the Preterm Infant Gut Microbiota and Metabolome: An Observational Study. Cell Reports Medicine. 1(5), pp. 100077-100077
2020. Cross-utilisation of template RNAs by alphavirus replicases. PLoS Pathogens. 16(9)
2020. Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy. Journal of the American Heart Association.
2020. RNA and the PIEZO force sensor. Cell Research. 30(10), pp. 829-830
2020. High-Quality Assemblies for Three Invasive Social Wasps from the Vespula Genus. G3: Genes, Genomes, Genetics.
2020. Advantages of CEMiTool for gene co-expression analysis of RNA-seq data. Computers in Biology and Medicine.
2020. Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease. Acta Neuropathologica Communications. 8
2020. A dichotomy of gene regulatory associations during the activated B-cell to plasmablast transition. Life Science Alliance. e202000654-e202000654 3.10
2020. Plastic male mating behaviour evolves in response to the competitive environment. Evolution.
2020. Ribosome Fingerprinting with a Solid-State Nanopore. ACS Sensors.
2020. Obese and hungry: two faces of a nation. British Medical Journal (BMJ). 370
2020. Long‐term performance of left ventricular leads in cardiac resynchronisation therapy. Pacing and Clinical Electrophysiology. 43(12), pp. 1501-1507
2020. Small molecule inhibitors possibly targeting the rearrangement of Zika virus Envelope protein. Antiviral Research.
2020. Prioritizing symptom management in the treatment of chronic heart failure. ESC Heart Failure. 7(5), pp. 2193-2207
2020. Mediation of Cardiac Macrophage Activity via Auricular Vagal Nerve Stimulation Ameliorates Cardiac Ischemia/Reperfusion Injury. Frontiers in Neuroscience. 14
2020. Plant Science Decadal Vision 2020-2030: Reimagining the Potential of Plants for a Healthy and Sustainable Future. Plant Direct. 4(8)
2020. Multiplex melanoma families are enriched for polygenic risk. Human Molecular Genetics.
2020. Histone deacetylase inhibitors induce medulloblastoma cell death independent of HDACs recruited in REST repression complexes. Molecular Genetics & Genomic Medicine. 8(10)
2020. Improvement in histological endpoints of MAFLD following a 12-week aerobic exercise intervention. Alimentary Pharmacology & Therapeutics.
2020. The Desotamide Family of Antibiotics. Antibiotics. 9(8)
2020. Natural remedies for Covid-19 as a driver of the illegal wildlife trade. Oryx. 54(5), pp. 601-602
2020. Identification of candidate mediators of chemoresponse in breast cancer through therapy-driven selection of somatic variants. Breast Cancer Research and Treatment. 183(3), pp. 607-616
2020. Novel universal primers for metabarcoding environmental DNA surveys of marine mammals and other marine vertebrates. Environmental DNA. 2(4), pp. 460-476
2020. Novel Thienopyrimidine Inhibitors of Leishmania N-Myristoyltransferase with On-Target Activity in Intracellular Amastigotes. Journal of Medicinal Chemistry. 7740-7765 63.14
2020. Merkel Cell Polyomavirus Small Tumor Antigen Activates Matrix Metallopeptidase-9 Gene Expression for Cell Migration and Invasion. Journal of Virology.
2020. Merkel cell polyomavirus small tumour antigen activates the p38 MAPK pathway to enhance cellular motility. Biochemical Journal. 477(14), pp. 2721-2733
2020. The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies?. FASEB Journal. 11015-11029 34.8
2020. TLR-mediated activation of Waldenström macroglobulinemia B cells reveals an uncoupling from plasma cell differentiation. Blood Advances. 2821-2836 4.12
2020. The diversity and distribution of D1 proteins in cyanobacteria. Photosynthesis Research. 145(2), pp. 111-128
2020. Multi-parent populations in crops: a toolbox integrating genomics and genetic mapping with breeding. Heredity.
2020. Temperature control of plant development. Annual Plant Reviews online. 3(4)
2020. Investigation of the Causal Association between Long-Chain n-6 Polyunsaturated Fatty Acid Synthesis and the Risk of Type 2 Diabetes: A Mendelian Randomization Analysis. Lifestyle Genomics.
2020. Alzheimer’s disease: the potential of epigenetic treatments and current clinical candidates. Neurodegenerative Disease Management. 10(3), pp. 543-558
2020. Host Gene Expression of Macrophages in Response to Feline Coronavirus Infection. Cells. 9(6)
2020. Response by Benitah et al to Letter Regarding Article, “Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload”. Circulation. 141(22), pp. e839-e840
2020. Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma. Nature Communications. 11(1)
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